The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally[S]
Cholesterol is essential to human health, and its levels are tightly regulated by a balance of synthesis, uptake, and efflux.Cholesterol synthesis requires the actions of more than twenty enzymes to reach the final product, through two alternate pathways.Here we describe a physical and functional interaction Little Boys Hoodies between the two term